Acetyl chloride → 3-({Acetyl-[3-(2-chloro-pyrimidin-4-yl)-benzyl]-amino}-methyl)-pyrrolidine-1-carboxylic acid tert-butyl ester

HRID 293825Notes

Reaction equation

HRID 293825 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH:10]([CH2:13][NH:14][CH2:15][c:16]2[cH:17][c:18](-[c:22]3[n:23][c:24]([Cl:28])[n:25][cH:26][cH:27]3)[cH:19][cH:20][cH:21]2)[CH2:11][CH2:12]1.[CH3:29][C:30]([Cl:31])=[O:32]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH:10]([CH2:13][N:14]([CH2:15][c:16]2[cH:17][c:18](-[c:22]3[n:23][c:24]([Cl:28])[n:25][cH:26][cH:27]3)[cH:19][cH:20][cH:21]2)[C:30]([CH3:29])=[O:32])[CH2:11][CH2:12]1

Participants

3

Reactant 2

HCID 6367Acetyl chlorideHCID 866032793-{[3-(2-Chloro-pyrimidin-4-yl)-benzylamino]-methyl}-pyrrolidine-1-carboxylic acid tert-butyl ester

Product 1

HCID 866032803-({Acetyl-[3-(2-chloro-pyrimidin-4-yl)-benzyl]-amino}-methyl)-pyrrolidine-1-carboxylic acid tert-butyl ester

Sources & evidence

ORD record
ord-da095e6614864aee882b2592f8091b46
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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