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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 293877Generated: October 26, 2026

Diethyl Ether → (3,4-Difluoro-phenyl)-propynoic acid ethyl ester

https://huagongshe.com/reaction/293877

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiethyl EtherHCID 3283—
ReactantTetrahydrofuranHCID 8028—
ReactantTriphenylphosphineHCID 11776—
ReactantEthyl propiolateHCID 12182—
ReactantPalladiumHCID 23938—
ReactantLithium ionHCID 28486—
Reactant1,2-Difluoro-4-iodobenzeneHCID 2724444—
ReactantDiisopropylamideHCID 5062348—
Product(3,4-Difluoro-phenyl)-propynoic acid ethyl esterHCID 58312680—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (8/10)
ORD IDord-a11ee84f8e8740b0b8e14127c66517b3
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (8/10)