HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 293893Generated: October 30, 2026
Dimethylformamide → 4-(8-(benzo[d][1,3]dioxol-5-ylmethyl)-8-aza-bicyclo[3.2.1]octan-3-ylamino)-6-chloro-1-(2,2,2-trifluoroethyl)quinazolin-2(1H)-one
https://huagongshe.com/reaction/293893
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Dimethylformamide | HCID 6228 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 1,3-Benzodioxole, 5-(chloromethyl)- | HCID 88713 | — |
| Reactant | 4-(8-Aza-bicyclo[3.2.1]oct-3-ylamino)-6-chloro-1-(2,2,2-trifluoro-ethyl)-1H-quinazolin-2-One | HCID 22348069 | — |
| Product | 4-(8-(benzo[d][1,3]dioxol-5-ylmethyl)-8-aza-bicyclo[3.2.1]octan-3-ylamino)-6-chloro-1-(2,2,2-trifluoroethyl)quinazolin-2(1H)-one | HCID 10075375 | — |
Provenance & Evidence
| DOI | 10.1039/C8SC04228D |
|---|
| Source dataset | Training data from https://doi.org/10.1039/C8SC04228D (8/10) |
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| ORD ID | ord-2047a6b8bc6f469aa06c266339ea9188 |
|---|
| Source note | Training data from https://doi.org/10.1039/C8SC04228D (8/10) |
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