Acetate → N2-(2-Methoxy-benzyl)-4-pyridin-3-yl-N6-pyridin-3-ylmethyl-quinoline-2,6-diamine

HRID 294124Notes

Reaction equation

HRID 294124 reaction equation
[C:43]([OH:44])([CH3:45])([CH3:46])[CH3:47].[C:48]([O-:49])(=[O:50])[CH3:51].[C:53]([O-:54])(=[O:55])[CH3:56].[CH3:36][c:37]1[cH:38][cH:39][cH:40][cH:41][cH:42]1.[Cl:1][c:2]1[cH:3][c:4]2[c:5](-[c:22]3[cH:23][n:24][cH:25][cH:26][cH:27]3)[cH:6][c:7]([NH:12][CH2:13][c:14]3[c:15]([O:20][CH3:21])[cH:16][cH:17][cH:18][cH:19]3)[n:8][c:9]2[cH:10][cH:11]1.[Pd+2:52].[cH:28]1[c:29]([CH2:34][NH2:35])[cH:30][cH:31][cH:32][n:33]1>>[c:2]1([NH:35][CH2:34][c:29]2[cH:28][n:33][cH:32][cH:31][cH:30]2)[cH:3][c:4]2[c:5](-[c:22]3[cH:23][n:24][cH:25][cH:26][cH:27]3)[cH:6][c:7]([NH:12][CH2:13][c:14]3[c:15]([O:20][CH3:21])[cH:16][cH:17][cH:18][cH:19]3)[n:8][c:9]2[cH:10][cH:11]1

Participants

7

Reactant 6

HCID 175Acetate2×HCID 1140TolueneHCID 6386tert-ButanolHCID 310183-PyridinemethanamineHCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 68574847(6-Chloro-4-pyridin-3-yl-quinolin-2-yl)-(2-methoxy-benzyl)-amine

Product 1

HCID 68574967N2-(2-Methoxy-benzyl)-4-pyridin-3-yl-N6-pyridin-3-ylmethyl-quinoline-2,6-diamine

Sources & evidence

ORD record
ord-733edc2097b14a6d8569372055bc8abe
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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