Dimethyl Sulfoxide → 1-[4-(7-chloro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]-3-(1H-indol-4-yloxy)propan-2-ol

HRID 294452Notes

Reaction equation

HRID 294452 reaction equation
[CH3:31][S:32]([CH3:33])=[O:34].[CH3:35][OH:36].[Cl:1][c:2]1[cH:3][cH:4][cH:5][c:6]2[c:7]([C:11]3=[CH:16][CH2:15][NH:14][CH2:13][CH2:12]3)[cH:8][nH:9][c:10]12.[O:17]1[CH:18]([CH2:20][O:21][c:22]2[c:23]3[cH:24][cH:25][nH:26][c:27]3[cH:28][cH:29][cH:30]2)[CH2:19]1>>[Cl:1][c:2]1[cH:3][cH:4][cH:5][c:6]2[c:7]([C:11]3=[CH:16][CH2:15][N:14]([CH2:19][CH:18]([OH:17])[CH2:20][O:21][c:22]4[c:23]5[cH:24][cH:25][nH:26][c:27]5[cH:28][cH:29][cH:30]4)[CH2:13][CH2:12]3)[cH:8][nH:9][c:10]12

Participants

5

Reactant 4

HCID 679Dimethyl SulfoxideHCID 887MethanolHCID 6050154-(oxiran-2-ylmethoxy)-1H-indoleHCID 185458497-chloro-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole

Product 1

HCID 212683501-[4-(7-chloro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]-3-(1H-indol-4-yloxy)propan-2-ol

Sources & evidence

ORD record
ord-76327f79295f469ea27c69e40776c4d4
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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