Trifluoroacetic acid methylene chloride → HCID 68715969, compound

HRID 29483Notes

Reaction equation

HRID 29483 reaction equation
C([O:5][C:6]([C:8]1[O:9][C:10]2[CH:17]=[CH:16][CH:15]=[C:14]([O:18][CH2:19][C:20]([O:22][CH3:23])=[O:21])[C:11]=2[C:12]=1[CH3:13])=[O:7])(C)(C)C.C(O)(C(F)(F)F)=O.C(Cl)Cl>>[CH3:23][O:22][C:20]([CH2:19][O:18][C:14]1[C:11]2[C:12]([CH3:13])=[C:8]([C:6]([OH:7])=[O:5])[O:9][C:10]=2[CH:17]=[CH:16][CH:15]=1)=[O:21]

Participants

3

Reactant 2

HCID 21863450Trifluoroacetic acid methylene chlorideHCID 687166324-Methoxycarbonylmethoxy-3-methyl-benzofuran-2-carboxylic acid tert-butyl ester

Product 1

HCID 68715969HCID 68715969, compound

Procedure

The above 4-methoxycarbonylmethoxy-3-methyl-benzofuran-2-carboxylic acid tert-butyl ester was dissolved into a 40% TFA/methylene chloride solution, and stirred at room temperature for 4 hours. Evaporation of the solvent gave 4-methoxycarbonylmethoxy-3-methyl-benzofuran-2-carboxylic acid in quantitative yield.

Workup

  1. customEvaporation of the solvent

Sources & evidence

ORD record
ord-771f1fe9308241ecb2072f5f968ad8fd
Source dataset
uspto-grants-2008_09
Patent number
US07420001B2

Reaction notes

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