Tetrahydrofuran → 4-Biphenylsulfonic acid, 4'-amino-

Participants

Reaction Steps

4′-Nitro-biphenyl-4-sulfonic acid (1.12 g, 4 mmol) was mixed with tin (II) chloride (5.2 g, 32 mmol) and 40 ml of THF. The mixture was refluxed overnight. The reaction mixture was poured into 80 ml of water and stirred at room temperature for 8 h. The mixture was filtered and the solid was dried under vacuum to provide 0.73 g (73%) of 4′-amino-biphenyl-4-sulfonic acid, obtained as an off-white solid.

Provenance & Evidence