1-(3,5-Difluorophenyl)piperazine → 1-[(2-Methoxyquinolin-3-yl)aminothiocarbonyl]-4-(3,5-difluorophenyl)piperazine
Reaction equation
[CH3:1][O:2][c:3]1[n:4][c:5]2[cH:6][cH:7][cH:8][cH:9][c:10]2[cH:11][c:12]1[NH:13][C:14]([O:15][c:16]1[cH:17][cH:18][cH:19][cH:20][cH:21]1)=[S:22].[F:23][c:24]1[cH:25][c:26]([N:31]2[CH2:32][CH2:33][NH:34][CH2:35][CH2:36]2)[cH:27][c:28]([F:30])[cH:29]1>>[CH3:1][O:2][c:3]1[n:4][c:5]2[cH:6][cH:7][cH:8][cH:9][c:10]2[cH:11][c:12]1[NH:13][C:14](=[S:22])[N:34]1[CH2:33][CH2:32][N:31]([c:26]2[cH:25][c:24]([F:23])[cH:29][c:28]([F:30])[cH:27]2)[CH2:36][CH2:35]1Participants
3
Sources & evidence
- ORD record
- ord-39560a2902fa4ca0b12b0575298dc7e1
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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