Acetic Acid → tert-butyl N-(4-amino-1-benzyl-3-hydroxy-5-phenyl-pentyl)carbamate

HRID 295270Notes

Reaction equation

HRID 295270 reaction equation
[CH2:1]([N:8]([CH2:2][c:3]1[cH:4][cH:5][cH:6][cH:7][cH:9]1)[CH:16]([CH2:17][c:18]1[cH:19][cH:20][cH:21][cH:22][cH:23]1)[CH:24]([CH2:25][CH:26]([CH2:27][c:28]1[cH:29][cH:30][cH:31][cH:32][cH:33]1)[NH:34][C:35](=[O:36])[O:37][C:38]([CH3:39])([CH3:40])[CH3:41])[OH:42])[c:10]1[cH:11][cH:12][cH:13][cH:14][cH:15]1.[CH3:47][C:48](=[O:49])[OH:50].[CH3:51][OH:52].[CH:43]([O-:44])=[O:45].[NH4+:46].[Pd:53]>>[NH2:8][CH:16]([CH2:17][c:18]1[cH:19][cH:20][cH:21][cH:22][cH:23]1)[CH:24]([CH2:25][CH:26]([CH2:27][c:28]1[cH:29][cH:30][cH:31][cH:32][cH:33]1)[NH:34][C:35](=[O:36])[O:37][C:38]([CH3:39])([CH3:40])[CH3:41])[OH:42]

Participants

7

Reactant 6

HCID 176Acetic AcidHCID 223AmmoniumHCID 283FormateHCID 887MethanolHCID 23938PalladiumHCID 18759120tert-butyl N-[5-(dibenzylamino)-4-hydroxy-1,6-diphenylhexan-2-yl]carbamate

Product 1

HCID 18758861tert-butyl N-(4-amino-1-benzyl-3-hydroxy-5-phenyl-pentyl)carbamate

Sources & evidence

ORD record
ord-048dc7352fcc4b59b02815233970358f
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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