3-Trifluoromethylcinnamic acid → N-[1-(5,5-difluorohexyl)pyrazol-3-yl]-3-[3-(trifluoromethyl)phenyl]prop-2-enamide
Reaction equation
[F:15][C:16]([c:17]1[cH:18][c:19]([CH:23]=[CH:24][C:25](=[O:26])[OH:27])[cH:20][cH:21][cH:22]1)([F:28])[F:29].[F:1][C:2]([CH2:3][CH2:4][CH2:5][CH2:6][n:7]1[n:8][c:9]([NH2:12])[cH:10][cH:11]1)([CH3:13])[F:14]>>[F:1][C:2]([CH2:3][CH2:4][CH2:5][CH2:6][n:7]1[n:8][c:9]([NH:12][C:25]([CH:24]=[CH:23][c:19]2[cH:18][c:17]([C:16]([F:15])([F:28])[F:29])[cH:22][cH:21][cH:20]2)=[O:26])[cH:10][cH:11]1)([CH3:13])[F:14]Participants
3
Sources & evidence
- ORD record
- ord-d1f382b70b604d93ac7946c8ee0394f0
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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