HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(1,3-Oxazol-5-yl)benzenesulphonyl chloride → N-[4-Chloro-2-(pyridine-3-carbonyl)-phenyl]4-oxazol-5-yl-benzenesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(1,3-Oxazol-5-yl)benzenesulphonyl chloride | HCID 2776415 | — |
| Reactant | (2-Amino-5-chlorophenyl)(pyridin-3-yl)methanone | HCID 13549723 | — |
| Product | N-[4-Chloro-2-(pyridine-3-carbonyl)-phenyl]4-oxazol-5-yl-benzenesulfonamide | HCID 10003341 | — |
Reaction Steps
The title compound was prepared according to the general procedure for the synthesis of N-Aryl-benzenesulfonamides previously described using 116 mg of (2-Amino-5-chloro-phenyl)-pyridin-3-yl-methanone and 122 mg of 4-oxazol-5-yl-benzenesulfonyl chloride. 1H-NMR (400 MHz, CDCl3): δ 7.23 (m, 2H), 7.42-7.47 (m, 3H), 7.58-7.62 (m, 3H), 7.71 (dt, 1H, J=7.6 Hz, 2.0 Hz), 7.88 (s,1H), 8.45 (b,1H), 8.58 (bd,1H, J=3.6 Hz), 9.67 (s,1H). MS: m/z 458.1 (M++1)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07420055B2 |
| Source dataset | uspto-grants-2008_09 |
| ORD ID | ord-df37cad39ce04b818dd855d796692345 |
| Source note | uspto-grants-2008_09 |