HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(1,3-Oxazol-5-yl)benzenesulphonyl chloride → N-[4-Chloro-2-(6-methyl-pyridine-2-carbonyl)-phenyl]-4-oxazol-5-yl-benzenesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(1,3-Oxazol-5-yl)benzenesulphonyl chloride | HCID 2776415 | — |
| Reactant | (2-Amino-5-chloro-phenyl)-(6-methyl-pyridin-2-yl)-methanone | HCID 22327312 | — |
| Product | N-[4-Chloro-2-(6-methyl-pyridine-2-carbonyl)-phenyl]-4-oxazol-5-yl-benzenesulfonamide | HCID 10004078 | — |
Reaction Steps
The title compound was prepared according to the general procedure for the synthesis of N-Aryl-benzenesulfonamides previously described using 123 mg of (2-Amino-5-chloro-phenyl)-(6-methyl-pyridin-2-yl)-methanone and 122 mg of 4-oxazol-5-yl-benzenesulfonyl chloride 1H-NMR (400 MHz, CDCl3): δ 2.67 (s, 3H), 7.46-7.50 (m, 4H), 7.61-7.70 (m, 4H), 7.65 (m, 2H), 7.94-8.00 (m, 1H), 8.15 (s, 1H). MS: m/z454.0 (M++1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07420055B2 |
| Source dataset | uspto-grants-2008_09 |
| ORD ID | ord-4412ad56f6a24468aa0fb04043c30732 |
| Source note | uspto-grants-2008_09 |