trans-N-[4-(Aminomethyl)cyclohexyl]-1H-benzimidazole-2-amine → tert-Butyl {2-[2-({[4-(1H-benzimidazol-2-ylamino)cyclohexyl]methyl}amino)-2-oxoethyl]-1-oxo-2,3,4,5-tetrahydro-1H-2-benzazepin-5-yl}acetate
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([CH2:7][CH:8]1[CH2:9][CH2:10][N:11]([CH2:20][C:21](=[O:22])[OH:23])[C:12](=[O:19])[c:13]2[c:14]1[cH:15][cH:16][cH:17][cH:18]2)=[O:24].[NH2:25][CH2:26][CH:27]1[CH2:28][CH2:29][CH:30]([NH:33][c:34]2[n:35][c:36]3[c:37]([nH:38]2)[cH:39][cH:40][cH:41][cH:42]3)[CH2:31][CH2:32]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([CH2:7][CH:8]1[CH2:9][CH2:10][N:11]([CH2:20][C:21](=[O:23])[NH:25][CH2:26][CH:27]2[CH2:28][CH2:29][CH:30]([NH:33][c:34]3[nH:35][c:36]4[c:37]([n:38]3)[cH:39][cH:40][cH:41][cH:42]4)[CH2:31][CH2:32]2)[C:12](=[O:19])[c:13]2[c:14]1[cH:15][cH:16][cH:17][cH:18]2)=[O:24]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-b00f8c37a06f4e57ad09f6e7a4f4ced7
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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