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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 295895Generated: October 30, 2026

Bicarbonate Ion → (3,5-Bis-trifluoromethyl-benzyl)-(2-fluoro-5-trifluoromethyl-benzyl)-(5-morpholin-4-yl-pyrimidin-2-yl)-amine

https://huagongshe.com/reaction/295895

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBicarbonate IonHCID 769—
ReactantSodium ionHCID 923—
ReactantTolueneHCID 1140—
ReactantMorpholineHCID 8083—
ReactantEthyl AcetateHCID 8857—
ReactantPalladiumHCID 23938—
ReactantDibenzylidene acetoneHCID 95417—
Reactant2-(Di-tert-butylphosphino)biphenylHCID 2734215—
Reactant2-Methylpropan-2-olateHCID 4574913—
Reactant(3,5-Bis-trifluoromethyl-benzyl)-(5-bromo-pyrimidin-2-yl)-(2-fluoro-5-trifluoromethyl-benzyl)-amineHCID 86626777—
Product(3,5-Bis-trifluoromethyl-benzyl)-(2-fluoro-5-trifluoromethyl-benzyl)-(5-morpholin-4-yl-pyrimidin-2-yl)-amineHCID 86626778—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (8/10)
ORD IDord-d0b0c18fff56441fa2293dc7a5f3e20a
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (8/10)