1-(4-chlorophenyl)-5-methyl-1H-pyrazole-4-carbonyl chloride → 1-(4-chlorophenyl)-N-[3-cyano-4-[4-(2-methoxyethyl)piperazin-1-yl]phenyl]-5-methylpyrazole-4-carboxamide

HRID 296096Notes

Reaction equation

HRID 296096 reaction equation
[Cl:1][c:2]1[cH:3][cH:4][c:5](-[n:8]2[n:9][cH:10][c:11]([C:14](=[O:15])[Cl:16])[c:12]2[CH3:13])[cH:6][cH:7]1.[NH2:17][c:18]1[cH:19][cH:20][c:21]([N:26]2[CH2:27][CH2:28][N:29]([CH2:32][CH2:33][O:34][CH3:35])[CH2:30][CH2:31]2)[c:22]([C:23]#[N:24])[cH:25]1>>[Cl:1][c:2]1[cH:3][cH:4][c:5](-[n:8]2[n:9][cH:10][c:11]([C:14](=[O:15])[NH:17][c:18]3[cH:19][cH:20][c:21]([N:26]4[CH2:27][CH2:28][N:29]([CH2:32][CH2:33][O:34][CH3:35])[CH2:30][CH2:31]4)[c:22]([C:23]#[N:24])[cH:25]3)[c:12]2[CH3:13])[cH:6][cH:7]1

Participants

3

Reactant 2

HCID 27761281-(4-chlorophenyl)-5-methyl-1H-pyrazole-4-carbonyl chlorideHCID 222279375-Amino-2-[4-(2-methoxyethyl)piperazin-1-yl]benzonitrile

Product 1

HCID 222279441-(4-chlorophenyl)-N-[3-cyano-4-[4-(2-methoxyethyl)piperazin-1-yl]phenyl]-5-methylpyrazole-4-carboxamide

Sources & evidence

ORD record
ord-3723afeed84e42a08f7ce44afc05f8a4
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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