4-(Propan-2-yl)benzene-1-sulfonyl chloride → N-[4-bromo-2-(pyridine-4-carbonyl)-phenyl]-4-isopropyl-benzenesulfonamide

HRID 29611Notes

Reaction equation

HRID 29611 reaction equation
[CH:1]([C:4]1[CH:9]=[CH:8][C:7]([S:10](Cl)(=[O:12])=[O:11])=[CH:6][CH:5]=1)([CH3:3])[CH3:2].[NH2:14][C:15]1[CH:20]=[CH:19][C:18]([Br:21])=[CH:17][C:16]=1[C:22]([C:24]1[CH:29]=[CH:28][N:27]=[CH:26][CH:25]=1)=[O:23]>>[Br:21][C:18]1[CH:19]=[CH:20][C:15]([NH:14][S:10]([C:7]2[CH:8]=[CH:9][C:4]([CH:1]([CH3:3])[CH3:2])=[CH:5][CH:6]=2)(=[O:12])=[O:11])=[C:16]([C:22]([C:24]2[CH:25]=[CH:26][N:27]=[CH:28][CH:29]=2)=[O:23])[CH:17]=1

Participants

3

Reactant 2

HCID 27348824-(Propan-2-yl)benzene-1-sulfonyl chlorideHCID 13549724(2-Amino-5-bromophenyl)(pyridin-4-yl)methanone

Product 1

HCID 59788715N-[4-bromo-2-(pyridine-4-carbonyl)-phenyl]-4-isopropyl-benzenesulfonamide

Procedure

The title compound was prepared according the general procedure for the synthesis of N-aryl-benzenesulfonamides using 4-isopropyl-benzenesulfonyl chloride and (2-amino-5-bromo-phenyl)-pyridin-4-yl-methanone and purified by HPLC. MS: m/z 460 (M++1).

Workup

  1. custompurified by HPLC

Sources & evidence

ORD record
ord-3eeab6dceb824ad49848c9a35c04e7be
Source dataset
uspto-grants-2008_09
Patent number
US07420055B2

Reaction notes

Loading…