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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 29613Generated: October 28, 2026

(2-Amino-5-chloro-phenyl)-(6-methyl-pyridin-3-yl)methanone → N-[4-cloro-2-(6-methyl-pyridine-3-carbonyl)-phenyl]-4-(2-methyl-oxazol-5-yl)-benzenesulfonamide

https://huagongshe.com/reaction/29613

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(2-Amino-5-chloro-phenyl)-(6-methyl-pyridin-3-yl)methanoneHCID 22327305—
Reactant4-(2-Methyl-1,3-oxazol-5-yl)benzenesulfonyl chlorideHCID 52997060—
ProductN-[4-cloro-2-(6-methyl-pyridine-3-carbonyl)-phenyl]-4-(2-methyl-oxazol-5-yl)-benzenesulfonamideHCID 59788755—

Reaction Steps

The title compound was prepared according to the general procedure for the preparation of N-aryl-benzenesulfonamides using 4-(2-methyl-oxazol-5-yl)-benzenesulfonyl chloride and (2-amino-5-chloro-phenyl)-(6-methyl-pyridin-3-yl)-methanone and purified by HPLC. MS: m/z 468.0 (M++1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07420055B2
Source datasetuspto-grants-2008_09
ORD IDord-58eda23173d0463f8af19f79a0ebb5c1
Source noteuspto-grants-2008_09