4-t-Butylbenzenesulfonyl chloride → 4-tert-Butyl-N-[3,4-difluoro-2-(pyridine-3-carbonyl)-phenyl]-benzenesulfonamide

HRID 29622Notes

Reaction equation

HRID 29622 reaction equation
[C:1]([C:5]1[CH:10]=[CH:9][C:8]([S:11](Cl)(=[O:13])=[O:12])=[CH:7][CH:6]=1)([CH3:4])([CH3:3])[CH3:2].[NH2:15][C:16]1[C:21]([C:22]([C:24]2[CH:25]=[N:26][CH:27]=[CH:28][CH:29]=2)=[O:23])=[C:20]([F:30])[C:19]([F:31])=[CH:18][CH:17]=1>>[C:1]([C:5]1[CH:10]=[CH:9][C:8]([S:11]([NH:15][C:16]2[CH:17]=[CH:18][C:19]([F:31])=[C:20]([F:30])[C:21]=2[C:22]([C:24]2[CH:25]=[N:26][CH:27]=[CH:28][CH:29]=2)=[O:23])(=[O:13])=[O:12])=[CH:7][CH:6]=1)([CH3:4])([CH3:3])[CH3:2]

Participants

3

Reactant 2

HCID 1398824-t-Butylbenzenesulfonyl chlorideHCID 59788582(6-Amino-2,3-difluoro-phenyl)-pyridin-3-yl-methanone

Product 1

HCID 597887114-tert-Butyl-N-[3,4-difluoro-2-(pyridine-3-carbonyl)-phenyl]-benzenesulfonamide

Procedure

The title compound was prepared by the reaction of 4-t-butylbenzenesulfonyl chloride with (6-Amino-2,3-difluoro-phenyl)-pyridin-3-yl-methanone following the general procedure. MS: m/z 431.1 (M++1).

Sources & evidence

ORD record
ord-066e2dce35464022b1d46616b64dcd9c
Source dataset
uspto-grants-2008_09
Patent number
US07420055B2

Reaction notes

Loading…