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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 29625Generated: October 26, 2026

(2-Amino-5-chlorophenyl)(pyridin-2-yl)methanone → N-[4-Chloro-2-(pyridine-2-carbonyl)-phenyl]-4-(4-methyl-tetrahydro-pyran-4-yl)-benzenesulfonamide

https://huagongshe.com/reaction/29625

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(2-Amino-5-chlorophenyl)(pyridin-2-yl)methanoneHCID 288049—
Reactant4-(4-Methyl-tetrahydro-pyran-4-yl)-benzenesulfonyl ChlorideHCID 59788600—
ProductN-[4-Chloro-2-(pyridine-2-carbonyl)-phenyl]-4-(4-methyl-tetrahydro-pyran-4-yl)-benzenesulfonamideHCID 59788556—

Reaction Steps

The title compound was prepared by the reacting 4-(4-methyl-tetrahydro-pyran-4-yl)-benzenesulfonyl chloride with (2-amino-5-chloro-phenyl)-pyridin-2-yl-methanone according to the general procedure described for the preparation of (N-aryl-benzenesulfonamides. MS: m/z 471 (M++1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07420055B2
Source datasetuspto-grants-2008_09
ORD IDord-10e8b2301d4643ceb94727c33776634a
Source noteuspto-grants-2008_09