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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 29627Generated: October 27, 2026

(2-Amino-5-chloro-phenyl)-(6-methyl-pyridin-3-yl)methanone → N-[4-Chloro-2-(6-methyl-pyridine-3-carbonyl)-phenyl]-4-(4-methyl-tetrahydro-pyran-4-yl)-benzenesulfonamide

https://huagongshe.com/reaction/29627

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(2-Amino-5-chloro-phenyl)-(6-methyl-pyridin-3-yl)methanoneHCID 22327305—
Reactant4-(4-Methyl-tetrahydro-pyran-4-yl)-benzenesulfonyl ChlorideHCID 59788600—
ProductN-[4-Chloro-2-(6-methyl-pyridine-3-carbonyl)-phenyl]-4-(4-methyl-tetrahydro-pyran-4-yl)-benzenesulfonamideHCID 59788759—

Reaction Steps

The title compound was prepared by the reacting 4-(4-methyl-tetrahydro-pyran-4-yl)-benzenesulfonyl chloride with (2-Amino-5-chloro-phenyl)-(6-methyl-pyridin-3-yl)-methanone according to the general procedure described for the preparation of (N-aryl-benzenesulfonamides. MS: m/z 486 (M++1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07420055B2
Source datasetuspto-grants-2008_09
ORD IDord-18f850d1ff1f492d8d5c553c212973dd
Source noteuspto-grants-2008_09