Dimethylamine → 2-[4-[2-[2-cyclopentyl-5-[(5,7-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)methyl]-4-hydroxy-6-oxo-3H-pyran-2-yl]ethyl]-2-fluoro-phenyl]-2-methyl-propanenitrile
Reaction equation
[BH3:44].[CH3:28][c:29]1[n:30][c:31]2[n:32]([c:33]([CH3:35])[cH:34]1)[n:36][c:37]([CH:39]=[O:40])[n:38]2.[CH3:41][NH:42][CH3:43].[CH3:45][OH:46].[CH:1]1([C:6]2([CH2:14][CH2:15][c:16]3[cH:17][c:18]([F:27])[c:19]([C:22]([C:23]#[N:24])([CH3:25])[CH3:26])[cH:20][cH:21]3)[O:7][C:8](=[O:13])[CH2:9][C:10](=[O:12])[CH2:11]2)[CH2:2][CH2:3][CH2:4][CH2:5]1>>[CH:1]1([C:6]2([CH2:14][CH2:15][c:16]3[cH:17][c:18]([F:27])[c:19]([C:22]([C:23]#[N:24])([CH3:25])[CH3:26])[cH:20][cH:21]3)[O:7][C:8](=[O:13])[C:9]([CH2:39][c:37]3[n:36][n:32]4[c:31]([n:30][c:29]([CH3:28])[cH:34][c:33]4[CH3:35])[n:38]3)=[C:10]([OH:12])[CH2:11]2)[CH2:2][CH2:3][CH2:4][CH2:5]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-8f32933262ad45afb9640d18ff807381
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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