(2-Amino-4,5-difluorophenyl)(pyridin-3-yl)methanone → HCID 59788548, compound

HRID 29633Notes

Reaction equation

HRID 29633 reaction equation
[NH2:1][C:2]1[CH:7]=[C:6]([F:8])[C:5]([F:9])=[CH:4][C:3]=1[C:10]([C:12]1[CH:13]=[N:14][CH:15]=[CH:16][CH:17]=1)=[O:11].[CH3:18][C:19]([C:26]1[CH:31]=[CH:30][C:29]([S:32](Cl)(=[O:34])=[O:33])=[CH:28][CH:27]=1)([C:21]1[O:22][CH:23]=[CH:24][N:25]=1)[CH3:20]>>[F:9][C:5]1[C:6]([F:8])=[CH:7][C:2]([NH:1][S:32]([C:29]2[CH:28]=[CH:27][C:26]([C:19]([CH3:20])([C:21]3[O:22][CH:23]=[CH:24][N:25]=3)[CH3:18])=[CH:31][CH:30]=2)(=[O:33])=[O:34])=[C:3]([C:10]([C:12]2[CH:13]=[N:14][CH:15]=[CH:16][CH:17]=2)=[O:11])[CH:4]=1

Participants

3

Reactant 2

HCID 59788583(2-Amino-4,5-difluorophenyl)(pyridin-3-yl)methanoneHCID 597886184-(1-Methyl-1-oxazol-2-yl-ethyl)-benzenesulfonyl chloride

Product 1

HCID 59788548HCID 59788548, compound

Procedure

The title compound was prepared from (2-Amino-4,5-difluoro-phenyl)-pyridin-3-yl-methanone and 4-(1-methyl-1-oxazol-2-yl-ethyl)-benzenesulfonyl chloride following the general procedure described for the preparation of N-aryl-benzenesulfonamides. MS: m/z 484 (M++1).

Sources & evidence

ORD record
ord-c55529e3a82a4f738270a4964e565a6d
Source dataset
uspto-grants-2008_09
Patent number
US07420055B2

Reaction notes

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