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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 296375Generated: October 27, 2026

Dichloromethane → 2-(Chloromethyl)-3-methyl-5-[4-(trifluoromethyl)phenyl]thiophene

https://huagongshe.com/reaction/296375

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDichloromethaneHCID 6344—
ReactantTriethylamineHCID 8471—
ReactantThionyl ChlorideHCID 24386—
Reactant[3-Methyl-5-(4-trifluoromethylphenyl)thien-2-yl]methanolHCID 21986444—
Product2-(Chloromethyl)-3-methyl-5-[4-(trifluoromethyl)phenyl]thiopheneHCID 15946281—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (8/10)
ORD IDord-4dc7369d31864b0386612dd71379b8eb
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (8/10)