Chloroform → 3'-({4-[(3,5-dioxo-1,2,4-oxadiazolidin-2-yl)methyl]phenoxy}methyl)-N-(1-ethylpiperidin-3-yl)-2-methylbiphenyl-4-carboxamide

HRID 296616Notes

Reaction equation

HRID 296616 reaction equation
[CH2:33]([CH3:34])[N:35]1[CH2:36][CH:37]([NH2:41])[CH2:38][CH2:39][CH2:40]1.[CH:42]([Cl:43])([Cl:44])[Cl:45].[O:1]=[c:2]1[n:3]([CH2:8][c:9]2[cH:10][cH:11][c:12]([O:13][CH2:14][c:15]3[cH:16][c:17](-[c:21]4[c:22]([CH3:30])[cH:23][c:24]([C:27](=[O:28])[OH:29])[cH:25][cH:26]4)[cH:18][cH:19][cH:20]3)[cH:31][cH:32]2)[o:4][c:5](=[O:7])[nH:6]1>>[O:1]=[c:2]1[n:3]([CH2:8][c:9]2[cH:10][cH:11][c:12]([O:13][CH2:14][c:15]3[cH:16][c:17](-[c:21]4[c:22]([CH3:30])[cH:23][c:24]([C:27](=[O:29])[NH:41][CH:37]5[CH2:36][N:35]([CH2:33][CH3:34])[CH2:40][CH2:39][CH2:38]5)[cH:25][cH:26]4)[cH:18][cH:19][cH:20]3)[cH:31][cH:32]2)[o:4][c:5](=[O:7])[nH:6]1

Participants

4

Reactant 3

HCID 6212ChloroformHCID 980943-amino-N-ethylpiperidineHCID 577873303'-({4-[(3,5-Dioxo-1,2,4-oxadiazolidin-2-yl)methyl]phenoxy}methyl)-2-methylbiphenyl-4-carboxylic acid

Product 1

HCID 577871073'-({4-[(3,5-dioxo-1,2,4-oxadiazolidin-2-yl)methyl]phenoxy}methyl)-N-(1-ethylpiperidin-3-yl)-2-methylbiphenyl-4-carboxamide

Sources & evidence

ORD record
ord-ab6615c376f04c0691148e61fefd2f32
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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