HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 296650Generated: October 26, 2026
Methanol → tert-butyl 1'-(8-(ethoxycarbonyl)-8-azabicyclo[3.2.1]octan-3-yl)-1H-spiro[isoquinoline-4,4'-piperidine]-2(3H)-carboxylate
https://huagongshe.com/reaction/296650
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | Sodium ion | HCID 923 | — |
| Reactant | Hydroxide | HCID 961 | — |
| Reactant | Dichloromethane | HCID 6344 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | Borohydride | HCID 28123 | — |
| Reactant | Titanium cation (4+) | HCID 114942 | — |
| Reactant | Ethyl 3-oxo-8-azabicyclo(3.2.1)octane-8-carboxylate | HCID 401882 | — |
| Reactant | Isopropanolate | HCID 3260420 | — |
| Reactant | tert-Butyl 1H-spiro[isoquinoline-4,4'-piperidine]-2(3H)-carboxylate | HCID 49760902 | — |
| Product | tert-butyl 1'-(8-(ethoxycarbonyl)-8-azabicyclo[3.2.1]octan-3-yl)-1H-spiro[isoquinoline-4,4'-piperidine]-2(3H)-carboxylate | HCID 58089822 | — |
Provenance & Evidence
| DOI | 10.1039/C8SC04228D |
|---|
| Source dataset | Training data from https://doi.org/10.1039/C8SC04228D (8/10) |
|---|
| ORD ID | ord-7a2ae268884249eebf7cc79ca2f9b747 |
|---|
| Source note | Training data from https://doi.org/10.1039/C8SC04228D (8/10) |
|---|
