Potassium Cation → 3-(1,1-Dioxidotetrahydro-2H-thiopyran-4-yl)-5-(1,3-thiazol-2-yl)-1H-indole-7-carboxamide

HRID 296708Notes

Reaction equation

HRID 296708 reaction equation
[Br:30][c:31]1[s:32][cH:33][cH:34][n:35]1.[C:36](=[O:37])([O-:38])[O-:39].[K+:40].[K+:41].[O:1]=[S:2]1(=[O:29])[CH2:3][CH2:4][CH:5]([c:8]2[cH:9][nH:10][c:11]3[c:12]([C:26](=[O:27])[NH2:28])[cH:13][c:14]([B:17]4[O:18][C:19]([CH3:20])([CH3:21])[C:22]([CH3:23])([CH3:24])[O:25]4)[cH:15][c:16]23)[CH2:6][CH2:7]1.[O:42]1[CH2:43][CH2:44][O:45][CH2:46][CH2:47]1.[OH2:48]>>[O:1]=[S:2]1(=[O:29])[CH2:3][CH2:4][CH:5]([c:8]2[cH:9][nH:10][c:11]3[c:12]([C:26](=[O:27])[NH2:28])[cH:13][c:14](-[c:31]4[s:32][cH:33][cH:34][n:35]4)[cH:15][c:16]23)[CH2:6][CH2:7]1

Participants

7

Reactant 6

HCID 813Potassium Cation2×HCID 962WaterHCID 19660Carbonate IonHCID 312751,4-DioxaneHCID 764302-BromothiazoleHCID 593327113-(1,1-dioxidotetrahydro-2H-thiopyran-4-yl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole-7-carboxamide

Product 1

HCID 593327273-(1,1-Dioxidotetrahydro-2H-thiopyran-4-yl)-5-(1,3-thiazol-2-yl)-1H-indole-7-carboxamide

Sources & evidence

ORD record
ord-b662d150d26347ef92ec647117401dea
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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