Thionyl Chloride → N-[3-(2-Chloro-5-cyano-pyrimidin-4-ylamino)-propyl]-3-nitro-benzenesulfonamide

HRID 296883Notes

Reaction equation

HRID 296883 reaction equation
[C:1]([CH3:3])([CH3:4])([NH:5][C:6](=[O:2])[c:8]1[c:9]([NH:15][CH2:16][CH2:17][CH2:18][NH:19][S:20](=[O:21])(=[O:22])[c:23]2[cH:24][c:25]([N+:29](=[O:30])[O-:31])[cH:26][cH:27][cH:28]2)[n:10][c:11]([Cl:14])[n:12][cH:13]1)[CH3:7].[S:32]([Cl:33])([Cl:34])=[O:35]>>[N:5]#[C:6][c:8]1[c:9]([NH:15][CH2:16][CH2:17][CH2:18][NH:19][S:20](=[O:21])(=[O:22])[c:23]2[cH:24][c:25]([N+:29](=[O:30])[O-:31])[cH:26][cH:27][cH:28]2)[n:10][c:11]([Cl:14])[n:12][cH:13]1

Participants

3

Reactant 2

HCID 24386Thionyl ChlorideHCID 590203532-Chloro-4-[3-(3-nitro-benzenesulfonylamino)-propylamino]-pyrimidine-5-carboxylic acid-tert-butylamide

Product 1

HCID 17986386N-[3-(2-Chloro-5-cyano-pyrimidin-4-ylamino)-propyl]-3-nitro-benzenesulfonamide

Sources & evidence

ORD record
ord-84c0afce88c849428dd7dbc74b637da8
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

Loading…