Methanol → 1-[2-Hydroxy-3-(2-methoxyphenyloxy)-propyl]-4-(2-anilino-ethylamino)-piperidine

HRID 296907Notes

Reaction equation

HRID 296907 reaction equation
[CH3:33][OH:34].[H:31][H:32].[NH2:21][CH2:22][CH2:23][NH:24][c:25]1[cH:26][cH:27][cH:28][cH:29][cH:30]1.[OH:1][CH:2]([CH2:3][N:4]1[CH2:5][CH2:6][C:7](=[O:10])[CH2:8][CH2:9]1)[CH2:11][O:12][c:13]1[c:14]([O:19][CH3:20])[cH:15][cH:16][cH:17][cH:18]1>>[OH:1][CH:2]([CH2:3][N:4]1[CH2:5][CH2:6][CH:7]([NH:21][CH2:22][CH2:23][NH:24][c:25]2[cH:26][cH:27][cH:28][cH:29][cH:30]2)[CH2:8][CH2:9]1)[CH2:11][O:12][c:13]1[c:14]([O:19][CH3:20])[cH:15][cH:16][cH:17][cH:18]1

Participants

5

Reactant 4

HCID 887MethanolHCID 742701,2-Ethanediamine, N1-phenyl-HCID 233473441-[2-Hydroxy-(2-methoxyphenyloxy)-propyl]-piperidin-4-oneHCID 178418361HCID 178418361, compound

Product 1

HCID 233473391-[2-Hydroxy-3-(2-methoxyphenyloxy)-propyl]-4-(2-anilino-ethylamino)-piperidine

Sources & evidence

ORD record
ord-1fb3940dd2d74dd9b88a85f1b45b8112
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

Loading…