2,4-Dichloro-6-cyclopropylpyrimidine → 2-chloro-6-cyclopropyl-N-(5-cyclopropyl-1H-pyrazol-3-yl)pyrimidin-4-amine

HRID 297118Notes

Reaction equation

HRID 297118 reaction equation
[Cl:12][c:13]1[n:14][c:15]([NH:19][c:20]2[cH:21][c:22]([CH:25]3[CH2:26][CH2:27]3)[n:23][nH:24]2)[c:16]([Cl:17])[cH:18][n:28]1.[Cl:1][c:2]1[n:3][c:4]([CH:9]2[CH2:10][CH2:11]2)[cH:5][c:6]([Cl:8])[n:7]1>>[Cl:1][c:2]1[n:3][c:4]([CH:9]2[CH2:10][CH2:11]2)[cH:5][c:6]([NH:19][c:20]2[cH:21][c:22]([CH:25]3[CH2:26][CH2:27]3)[nH:23][n:24]2)[n:7]1

Participants

3

Reactant 2

HCID 223090852,4-Dichloro-6-cyclopropylpyrimidineHCID 178478344HCID 178478344, compound

Product 1

HCID 875856602-chloro-6-cyclopropyl-N-(5-cyclopropyl-1H-pyrazol-3-yl)pyrimidin-4-amine

Sources & evidence

ORD record
ord-352d9ade93164331b96b7aece247fbf1
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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