6-chloro-N-(4-methoxyphenyl)nicotinamide → N-(4-Methoxyphenyl)-6-[2-methyl-5-(thiazol-2-ylcarbamoyl)-phenyl]-nicotinamide

HRID 297157Notes

Reaction equation

HRID 297157 reaction equation
[CH3:19][c:20]1[c:21]([B:34]2[O:35][C:36]([CH3:37])([CH3:38])[C:39]([CH3:40])([CH3:41])[O:42]2)[cH:22][c:23]([C:24](=[O:25])[NH:26][c:27]2[s:28][cH:29][cH:30][n:31]2)[cH:32][cH:33]1.[Cl:1][c:2]1[n:3][cH:4][c:5]([C:6](=[O:7])[NH:8][c:9]2[cH:10][cH:11][c:12]([O:15][CH3:16])[cH:13][cH:14]2)[cH:17][cH:18]1>>[c:2]1(-[c:21]2[c:20]([CH3:19])[cH:33][cH:32][c:23]([C:24](=[O:25])[NH:26][c:27]3[s:28][cH:29][cH:30][n:31]3)[cH:22]2)[n:3][cH:4][c:5]([C:6](=[O:7])[NH:8][c:9]2[cH:10][cH:11][c:12]([O:15][CH3:16])[cH:13][cH:14]2)[cH:17][cH:18]1

Participants

3

Reactant 2

HCID 14832696-chloro-N-(4-methoxyphenyl)nicotinamideHCID 219145174-Methyl-3-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-N-(thiazol-2-yl)-benzamide

Product 1

HCID 21914585N-(4-Methoxyphenyl)-6-[2-methyl-5-(thiazol-2-ylcarbamoyl)-phenyl]-nicotinamide

Sources & evidence

ORD record
ord-e0ff6858c2b44e73bdd951170b058046
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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