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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 297239Generated: October 27, 2026

Toluene → Methyl 4,4-difluoro-3-oxo-2-(2,6-dimethylmorpholin-4-ylmethylidene)butyrate

https://huagongshe.com/reaction/297239

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTolueneHCID 1140—
ReactantTriethylamineHCID 8471—
Reactant2,2-Difluoroacetyl fluorideHCID 2778914—
ReactantHCID 66948531HCID 66948531—
ProductMethyl 4,4-difluoro-3-oxo-2-(2,6-dimethylmorpholin-4-ylmethylidene)butyrateHCID 86651361—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (8/10)
ORD IDord-1246a3ace6574b06aa6b96aba73a8801
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (8/10)