HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanol → N-(4-{[(4-aminophenyl)amino]methyl}benzyl)benzene-1,4-diamine tetrahydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | Water | HCID 962 | — |
| Reactant | Ammonium Chloride | HCID 25517 | — |
| Reactant | 4-nitro-N-(4-{[(4-nitrophenyl)amino]methyl}benzyl)aniline | HCID 23656762 | — |
| Catalyst | Zinc | HCID 23994 | — |
| Solvent | N-methyl-2-pyrrolidone | HCID 13387 | — |
| Product | N-(4-{[(4-aminophenyl)amino]methyl}benzyl)benzene-1,4-diamine tetrahydrochloride | HCID 69252903 | — |
Reaction Steps
The mixture of powdered zinc (22.2 g), ammonium chloride (2.5 g), water (4 ml) and absolute ethanol (20 ml) were brought to reflux with the oil bath. The 4-nitro-N-(4-{[(4-nitrophenyl)amino]methyl}benzyl)aniline (3.4 g) was dissolved in 20 ml of NMP and introduced dropwise until there was decoloration of the reaction medium, while at the same time the reflux was maintained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07422609B2 |
| Source dataset | uspto-grants-2008_09 |
| ORD ID | ord-210702c204ef409592efd42d6c840278 |
| Source note | uspto-grants-2008_09 |