Acetyl chloride → HCID 69197666, compound

HRID 29773Notes

Reaction equation

[C:1](Cl)(=[O:3])[CH3:2].Cl.[O:6]=[S:7]1(=[O:29])[C:12]2[CH:13]=[C:14]([O:17][C:18]3[CH:23]=[CH:22][C:21]([CH2:24][NH2:25])=[CH:20][CH:19]=3)[CH:15]=[CH:16][C:11]=2[N:10]2[CH2:26][CH2:27][CH2:28][CH:9]2[NH:8]1>>[O:29]=[S:7]1(=[O:6])[C:12]2[CH:13]=[C:14]([O:17][C:18]3[CH:23]=[CH:22][C:21]([CH2:24][NH:25][C:1](=[O:3])[CH3:2])=[CH:20][CH:19]=3)[CH:15]=[CH:16][C:11]=2[N:10]2[CH2:26][CH2:27][CH2:28][CH:9]2[NH:8]1

Participants

Reactant 2

HCID 6367Acetyl chloride

HCID 691992861-{4-[(5,5-Dioxido-2,3,3a,4-tetrahydro-1H-pyrrolo[2,1-c][1,2,4]-benzothiadiazin-7-yl)oxy]phenyl}methanamine hydrochloride

Product 1

HCID 69197666HCID 69197666, compound

Procedure

The procedure is as in Example 2, replacing the methanesulphonic anhydride by acetyl chloride and using as starting material the amine obtained in Example 20.

Sources & evidence

ORD record: ord-2c4ec6494b8a4ff0a3db3f1c18d00b55
Source dataset: uspto-grants-2008_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07423034B2

Reaction notes

Loading…