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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 297788Generated: October 30, 2026

Toluene → 4-Hydroxy-6-methyl-3-(4,4,4-trifluorobutanoyl)-2H-pyran-2-one

https://huagongshe.com/reaction/297788

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTolueneHCID 1140—
ReactantDicyclohexylcarbodiimideHCID 10868—
Reactant4-(Dimethylamino)pyridineHCID 14284—
Reactant4,4,4-Trifluorobutanoic acidHCID 2777085—
Reactant4-Hydroxy-6-methyl-2-pyroneHCID 54675757—
Product4-Hydroxy-6-methyl-3-(4,4,4-trifluorobutanoyl)-2H-pyran-2-oneHCID 59033171—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (8/10)
ORD IDord-ca2d511f0cee4ffea0a386469c2f0994
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (8/10)