Dichloromethane → 3-(6-benzyloxy-pyridin-3-yl)-2-{[4-(2-oxo-1,4-dihydro-2H-quinazolin-3-yl)-piperidine-1-carbonyl]-amino}-propionic acid methyl ester
Reaction equation
[C:22](=[O:23])([c:24]1[nH:25][cH:26][cH:27][n:28]1)[c:29]1[nH:30][cH:31][cH:32][n:33]1.[CH2:51]([Cl:52])[Cl:53].[CH3:1][O:2][C:3]([CH:4]([CH2:5][c:6]1[cH:7][n:8][c:9]([O:12][CH2:13][c:14]2[cH:15][cH:16][cH:17][cH:18][cH:19]2)[cH:10][cH:11]1)[NH2:20])=[O:21].[NH:34]1[CH2:35][CH2:36][CH:37]([N:40]2[C:41](=[O:50])[NH:42][c:43]3[cH:44][cH:45][cH:46][cH:47][c:48]3[CH2:49]2)[CH2:38][CH2:39]1>>[CH3:1][O:2][C:3]([CH:4]([CH2:5][c:6]1[cH:7][n:8][c:9]([O:12][CH2:13][c:14]2[cH:15][cH:16][cH:17][cH:18][cH:19]2)[cH:10][cH:11]1)[NH:20][C:22](=[O:23])[N:34]1[CH2:35][CH2:36][CH:37]([N:40]2[C:41](=[O:50])[NH:42][c:43]3[cH:44][cH:45][cH:46][cH:47][c:48]3[CH2:49]2)[CH2:38][CH2:39]1)=[O:21]Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-f77b2d023bd048c7b6f45506b0e03d9a
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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