Trifluoroacetate → HCID 11654317, compound

HRID 29836Notes

Reaction equation

HRID 29836 reaction equation
C([O:8][C:9]1[C:14]2[NH:15][C:16](=[O:19])[CH2:17][O:18][C:13]=2[C:12]([C:20](=[O:24])[CH:21](O)O)=[CH:11][CH:10]=1)C1C=CC=CC=1.[CH:25]1[C:34]2[C:29](=[CH:30][CH:31]=[CH:32][CH:33]=2)[CH:28]=[CH:27][C:26]=1[CH2:35][C:36]1([NH2:39])[CH2:38][CH2:37]1.FC(F)(F)C([O-])=O>>[OH:8][C:9]1[C:14]2[NH:15][C:16](=[O:19])[CH2:17][O:18][C:13]=2[C:12]([CH:20]([OH:24])[CH2:21][NH:39][C:36]2([CH2:35][C:26]3[CH:27]=[CH:28][C:29]4[C:34](=[CH:33][CH:32]=[CH:31][CH:30]=4)[CH:25]=3)[CH2:38][CH2:37]2)=[CH:11][CH:10]=1

Participants

4

Reactant 3

HCID 84468TrifluoroacetateHCID 231061485-(benzyloxy)-8-(dihydroxyacetyl)-2H-1,4-benzoxazin-3(4H)-oneHCID 552653591-[(Naphthalen-2-yl)methyl]cyclopropan-1-amine

Product 1

HCID 11654317HCID 11654317, compound

Procedure

Prepared according to general method 3 from 329 mg (1 mmol) 5-benzyloxy-8-(2,2-dihydroxy-acetyl)-4H-benzo[1,4]oxazin-3-one and 197 mg (1 mmol) 1-naphthalen-2-ylmethyl-cyclopropylamine. Yield: 20 mg (5%, trifluoroacetate); mass spectroscopy: [M+H]+=405.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-fe1cc48fd7d247cca9b482725c567820
Source dataset
uspto-grants-2008_09
Patent number
US07423035B2

Reaction notes

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