Potassium Cation → 1-Benzyl-4-hydroxy-piperidine-4-carboxylic acid methyl-(4-trifluoromethoxy-phenyl)-amide

HRID 298381Notes

Reaction equation

HRID 298381 reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[CH2:9][CH2:10][C:11]([C:14]([N:15]([c:16]2[cH:17][cH:18][c:19]([O:22][C:23]([F:24])([F:25])[F:26])[cH:20][cH:21]2)[CH3:27])=[O:28])([O:29][C:30](=[O:31])[CH3:32])[CH2:12][CH2:13]1.[K+:38].[S:33](=[O:34])(=[O:35])([OH:36])[O-:37]>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[CH2:9][CH2:10][C:11]([C:14]([N:15]([c:16]2[cH:17][cH:18][c:19]([O:22][C:23]([F:24])([F:25])[F:26])[cH:20][cH:21]2)[CH3:27])=[O:28])([OH:29])[CH2:12][CH2:13]1

Participants

4

Reactant 3

HCID 813Potassium CationHCID 61778Sulfate, hydrogenHCID 58129329Acetic acid 1-benzyl-4-[methyl-(4-trifluoromethoxy-phenyl)-carbamoyl]-piperidin-4-yl ester

Product 1

HCID 581293421-Benzyl-4-hydroxy-piperidine-4-carboxylic acid methyl-(4-trifluoromethoxy-phenyl)-amide

Sources & evidence

ORD record
ord-298d74a6925e4c8eb446da92d9cf91f5
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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