HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetate → 4-[2-(1-Benzyl-cyclopropylamino)-1-hydroxy-ethyl]-2-hydroxymethyl-phenol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetate | HCID 84468 | — |
| Reactant | 1-Benzylcyclopropylamine | HCID 152923 | — |
| Reactant | Methyl benzyloxy-5-(2-ethoxy-2-hydroxy-acetyl)-benzoate | HCID 68858509 | — |
| Product | 4-[2-(1-Benzyl-cyclopropylamino)-1-hydroxy-ethyl]-2-hydroxymethyl-phenol | HCID 11573217 | — |
Reaction Steps
Prepared according to general method 5 from 344 mg (1 mmol) methyl 2-benzyloxy-5-(2-ethoxy-2-hydroxy-acetyl)-benzoate and 147 mg (1 mmol) 1-benzyl-cyclopropylamine. Yield: 184 mg (43%, trifluoroacetate); mass spectroscopy: [M+H]+=314.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07423035B2 |
| Source dataset | uspto-grants-2008_09 |
| ORD ID | ord-94fd441b856b4ad28e1d48d86cfcbbc3 |
| Source note | uspto-grants-2008_09 |