Dimethylamine → (5-Chloro-6-{4-[6-(4-fluoro-phenyl)-2-(2-methyl-pyrrolidin-1-yl)-pyrimidin-4-yl]-piperazin-1-yl}-pyridin-3-ylmethyl)-dimethyl-amine
Reaction equation
[CH3:39][NH:40][CH3:41].[Cl:1][c:2]1[cH:3][c:4]([CH2:33][O:34][S:35]([CH3:36])(=[O:37])=[O:38])[cH:5][n:6][c:7]1[N:8]1[CH2:9][CH2:10][N:11]([c:14]2[n:15][c:16]([N:27]3[CH:28]([CH3:32])[CH2:29][CH2:30][CH2:31]3)[n:17][c:18](-[c:20]3[cH:21][cH:22][c:23]([F:26])[cH:24][cH:25]3)[cH:19]2)[CH2:12][CH2:13]1>>[Cl:1][c:2]1[cH:3][c:4]([CH2:33][N:40]([CH3:39])[CH3:41])[cH:5][n:6][c:7]1[N:8]1[CH2:9][CH2:10][N:11]([c:14]2[n:15][c:16]([N:27]3[CH:28]([CH3:32])[CH2:29][CH2:30][CH2:31]3)[n:17][c:18](-[c:20]3[cH:21][cH:22][c:23]([F:26])[cH:24][cH:25]3)[cH:19]2)[CH2:12][CH2:13]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-441e492d07b248c69959d6b77e7468c9
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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