HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetate → 6-hydroxy-8-{1-hydroxy-2-[1-(4-hydroxy-benzyl)-cyclopropylamino]-ethyl}-4H-benzo[1,4]oxazin-3-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetate | HCID 84468 | — |
| Reactant | HCID 22063474 | HCID 22063474 | — |
| Reactant | 1-(4-Benzyloxy-benzyl)-cyclopropylamine | HCID 23106121 | — |
| Product | 6-hydroxy-8-{1-hydroxy-2-[1-(4-hydroxy-benzyl)-cyclopropylamino]-ethyl}-4H-benzo[1,4]oxazin-3-one | HCID 23106151 | — |
Reaction Steps
Prepared according to general method 3 from 357 mg (1 mmol) 6-benzyloxy-8-(2-ethoxy-2-hydroxy-acetyl)-4H-benzo[1,4]oxazin-3-one and 253 mg (1 mmol) 1-(4-benzyloxy-benzyl)-cyclopropylamine. Yield: 47 mg (10%, trifluoroacetate); mass spectroscopy: [M+H]+=371.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07423035B2 |
| Source dataset | uspto-grants-2008_09 |
| ORD ID | ord-b940c21174b14ac8ad833106f2147ca3 |
| Source note | uspto-grants-2008_09 |