HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrazine hydrate (1:1) → 3-[2-(4-Aminophenyl)ethyl]-8-benzyl-1-propylxanthine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrazine hydrate (1:1) | HCID 24654 | — |
| Reactant | 8-Benzyl-3-[2-(4-nitrophenyl)ethyl]-1-propylxanthine | HCID 10365571 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Product | 3-[2-(4-Aminophenyl)ethyl]-8-benzyl-1-propylxanthine | HCID 9909146 | — |
Reaction Steps
By methods well known in the art, 8-benzyl-3-[2-(4-nitrophenyl)ethyl]-1-propylxanthine (9) is reduced with hydrazine hydrate or hydrogen gas in the presence of a palladium catalyst to yield 3-[2-(4-aminophenyl)ethyl]-8-benzyl-1-propylxanthine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07423041B2 |
| Source dataset | uspto-grants-2008_09 |
| ORD ID | ord-b8e5a392a1284771a205938f5e5be545 |
| Source note | uspto-grants-2008_09 |