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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 29877Generated: October 25, 2026

Phenylacetic Acid → 8-Benzyl-3-[2-(3-carboxyphenyl)ethyl]-1-propylxanthine

https://huagongshe.com/reaction/29877

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPhenylacetic AcidHCID 999—
Reactant5,6-Diamino-1-[2-(3-carboxyphenyl)ethyl]-3-propyluracilHCID 18449526—
Product8-Benzyl-3-[2-(3-carboxyphenyl)ethyl]-1-propylxanthineHCID 10071457—

Reaction Steps

By the method of Example 2, phenylacetic acid is reacted with 5,6-diamino-1-[2-(3-carboxyphenyl)ethyl]-3-propyluracil to yield 8-benzyl-3-[2-(3-carboxyphenyl)ethyl]-1-propylxanthine. In turn, 5,6-diamino-1-[2-(3-carboxyphenyl)ethyl]-3-propyluracil is made by the synthetic methods of Example 1, starting with 3-carboxyphenethylamine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07423041B2
Source datasetuspto-grants-2008_09
ORD IDord-869ecfbdc8334f0b994f426f36fc0aef
Source noteuspto-grants-2008_09