Ethanol → ethyl 6-amino-5-methyl-1,3,4,5-tetrahydro-2H-pyrido[4,3-b]indole-2-carboxylate

HRID 298959Notes

Reaction equation

HRID 298959 reaction equation
[CH3:1][n:2]1[c:3]2[c:4]([c:5]3[cH:6][cH:7][cH:8][c:9]([N+:11]([O-:12])=[O:13])[c:10]13)[CH2:14][N:15]([C:18](=[O:19])[O:20][CH2:21][CH3:22])[CH2:16][CH2:17]2.[CH3:23][CH2:24][OH:25].[OH-:26].[OH-:28].[Pd+2:27]>>[CH3:1][n:2]1[c:3]2[c:4]([c:5]3[cH:6][cH:7][cH:8][c:9]([NH2:11])[c:10]13)[CH2:14][N:15]([C:18](=[O:19])[O:20][CH2:21][CH3:22])[CH2:16][CH2:17]2

Participants

5

Reactant 4

HCID 702EthanolHCID 961Hydroxide2×HCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 68815911Ethyl 5-methyl-6-nitro-1,3,4,5-tetrahydro-2H-pyrido[4,3-b]indole-2-carboxylate

Product 1

HCID 68816953ethyl 6-amino-5-methyl-1,3,4,5-tetrahydro-2H-pyrido[4,3-b]indole-2-carboxylate

Sources & evidence

ORD record
ord-ea5664b1331740ddbda4b1b5ea194862
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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