Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 29899Generated: October 26, 2026

4-Fluorobenzyl bromide → 4-[(4-Fluorobenzyl)oxy]-2-phenyl-6,7-dihydro-5H-cyclopenta[d]pyrimidine

https://huagongshe.com/reaction/29899

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Fluorobenzyl bromideHCID 68021—
ReactantHCID 178517455HCID 178517455—
Product4-[(4-Fluorobenzyl)oxy]-2-phenyl-6,7-dihydro-5H-cyclopenta[d]pyrimidineHCID 11723523—

Reaction Steps

The title compound was prepared from 2-phenyl-6,7-dihydro-5H-cyclopentapyrimidin-4-ol (which was obtained in Intermediate 5) and 4-fluorobenzyl bromide according to Method A; LC retention time 3.26 min; MS: m/z (ESI) 321 (M+H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07423044B2
Source datasetuspto-grants-2008_09
ORD IDord-427b996b8384497b91c8121c533f3034
Source noteuspto-grants-2008_09