Dichloromethane → Piclamilast

HRID 299029Notes

Reaction equation

HRID 299029 reaction equation
[CH:10]1([O:15][c:16]2[cH:17][c:18]([C:19](=[O:20])[Cl:21])[cH:22][cH:23][c:24]2[O:25][CH3:26])[CH2:11][CH2:12][CH2:13][CH2:14]1.[Cl:27][CH2:28][Cl:29].[NH2:1][c:2]1[c:3]([Cl:9])[cH:4][n:5][cH:6][c:7]1[Cl:8]>>[NH:1]([c:2]1[c:3]([Cl:9])[cH:4][n:5][cH:6][c:7]1[Cl:8])[C:19]([c:18]1[cH:17][c:16]([O:15][CH:10]2[CH2:11][CH2:12][CH2:13][CH2:14]2)[c:24]([O:25][CH3:26])[cH:23][cH:22]1)=[O:20]

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 898884-Amino-3,5-dichloropyridineHCID 27946003-(Cyclopentyloxy)-4-methoxybenzoyl chloride

Product 1

HCID 154575Piclamilast

Sources & evidence

ORD record
ord-9528a8adfd5c4892911314cadada4400
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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