HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(Bromomethyl)benzonitrile → 4-({[6-Benzyl-2-(3,5-dichlorophenyl)-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-4-yl]oxy}methyl)benzonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(Bromomethyl)benzonitrile | HCID 86996 | — |
| Reactant | HCID 178517513 | HCID 178517513 | — |
| Product | 4-({[6-Benzyl-2-(3,5-dichlorophenyl)-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-4-yl]oxy}methyl)benzonitrile | HCID 69197822 | — |
Reaction Steps
The title compound was prepared from 6-benzyl-2-(3,5-dichloro-phenyl)-5,6,7,8-tetrahydro-pyrido[4,3-d]pyrimidin4-ol (which was obtained in Intermediate 7) and 4-cyanobenzyl bromide according to Method A; LC retention time 3.01 min; MS: m/z (ESI) 501 (M+H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07423044B2 |
| Source dataset | uspto-grants-2008_09 |
| ORD ID | ord-ca0fbd2cbd06433fbbd5408ecdd7862d |
| Source note | uspto-grants-2008_09 |