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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 29908Generated: October 27, 2026

4-(Bromomethyl)benzonitrile → 4-({[6-Isopropyl-2-(3-nitrophenyl)pyrimidin-4-yl]oxy}methyl)benzonitrile

https://huagongshe.com/reaction/29908

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(Bromomethyl)benzonitrileHCID 86996—
ReactantHCID 178439455HCID 178439455—
Product4-({[6-Isopropyl-2-(3-nitrophenyl)pyrimidin-4-yl]oxy}methyl)benzonitrileHCID 10362033—

Reaction Steps

The title compound was prepared from 6-isopropyl-2-(3-nitro-phenyl)-pyrimidin-4-ol (which was obtained in Intermediate 8) and 4-cyanobenzyl bromide according to Method A; LC retention time 3.71 min; MS: m/z (ESI) 375 (M+H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07423044B2
Source datasetuspto-grants-2008_09
ORD IDord-cac1865cb15f4dab82dc8f76eb3c6111
Source noteuspto-grants-2008_09