Pyridine → propan-2-yl 4-acetamido-6-methoxy-2-methyl-3,4-dihydro-2H-1,5-naphthyridine-1-carboxylate

HRID 299094Notes

Reaction equation

HRID 299094 reaction equation
[CH3:8][O:9][c:10]1[n:11][c:12]2[c:17]([cH:18][cH:19]1)[NH:16][CH:15]([CH3:20])[CH2:14][CH:13]2[NH:21][C:22]([CH3:23])=[O:24].[Cl:1][C:2](=[O:3])[O:4][CH:5]([CH3:6])[CH3:7].[Cl:31][CH2:32][Cl:33].[cH:25]1[cH:26][cH:27][n:28][cH:29][cH:30]1>>[C:2](=[O:3])([O:4][CH:5]([CH3:6])[CH3:7])[N:16]1[CH:15]([CH3:20])[CH2:14][CH:13]([NH:21][C:22]([CH3:23])=[O:24])[c:12]2[n:11][c:10]([O:9][CH3:8])[cH:19][cH:18][c:17]21

Participants

5

Reactant 4

HCID 1049PyridineHCID 6344DichloromethaneHCID 7917Isopropyl chloroformateHCID 58926730N-(6-methoxy-2-methyl-1,2,3,4-tetrahydro-1,5-naphthyridin-4-yl)acetamide

Product 1

HCID 58926732propan-2-yl 4-acetamido-6-methoxy-2-methyl-3,4-dihydro-2H-1,5-naphthyridine-1-carboxylate

Sources & evidence

ORD record
ord-591fc1de5ca54cb5b0164ed111917296
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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