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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 299169Generated: October 29, 2026

Formaldehyde → (+/-)-5-chloro-7-(1-((4-(4-fluorophenyl)-1-methylpiperidin-4-yl)methoxy)ethyl)-1H-indole-3-carbonitrile

https://huagongshe.com/reaction/299169

Reaction equation

Participants

RoleNameHCIDCharge
ReactantFormaldehydeHCID 712—
ReactantSodium ionHCID 923—
ReactantTrifluoroacetic acidHCID 6422—
ReactantTriethylamineHCID 8471—
ReactantTriacetoxyborohydrideHCID 2724942—
Reactant(+/-)-tert-butyl 4-((1-(5-chloro-3-cyano-1H-indol-7-yl)ethoxy)methyl)-4-(4-fluorophenyl)piperidine-1-carboxylateHCID 57545997—
Product(+/-)-5-chloro-7-(1-((4-(4-fluorophenyl)-1-methylpiperidin-4-yl)methoxy)ethyl)-1H-indole-3-carbonitrileHCID 25159528—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (8/10)
ORD IDord-d1cede0a6a4141eba8a7914ed2ec005c
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (8/10)