Ethanol → Trans-[4-Amino-2-(4-pyrrolidin-1-yl-cyclohexylamino)-pyrimidin-5-yl]-(2,3-difluoro-6-methoxy-phenyl)-methanone
Reaction equation
[Br:34][CH2:35][CH2:36][CH2:37][CH2:38][Br:39].[CH3:40][CH2:41][OH:42].[NH2:1][c:2]1[n:3][c:4]([NH:20][CH:21]2[CH2:22][CH2:23][CH:24]([NH2:27])[CH2:25][CH2:26]2)[n:5][cH:6][c:7]1[C:8](=[O:9])[c:10]1[c:11]([F:19])[c:12]([F:18])[cH:13][cH:14][c:15]1[O:16][CH3:17].[Na+:28].[Na+:29].[O-:30][C:31](=[O:32])[O-:33]>>[NH2:1][c:2]1[n:3][c:4]([NH:20][CH:21]2[CH2:22][CH2:23][CH:24]([N:27]3[CH2:35][CH2:36][CH2:37][CH2:38]3)[CH2:25][CH2:26]2)[n:5][cH:6][c:7]1[C:8](=[O:9])[c:10]1[c:11]([F:19])[c:12]([F:18])[cH:13][cH:14][c:15]1[O:16][CH3:17]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-213dc56a63be48fea255ae9bffd855bb
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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